Keywords

Quick Details

• ProName: Vismodegib
• CasNo: 879085-55-9
• Molecular Formula: C19H14Cl2N2O3S
• Purity: >99%
• LimitNum: 0

Superiority

Vismodegib(GDC-0449) Technical Data: M.Wt: 421.3 Formula: C19H14Cl2N2O3S Solubility: DMSO, Methanol Storage Conditions :2oC to 8oC, or -20oCfor…

Details

Vismodegib(GDC-0449) Technical Data: M.Wt: 421.3 Formula: C19H14Cl2N2O3S Solubility: DMSO, Methanol Storage Conditions :2oC to 8oC, or -20oCfor long-term storage Biological Activity: The first-in-class inhibitor of Hedgehog (Hh) signaling pathway; more specifically, an orally bioavailable and potent inhibitor of smoothened homologue (SMO); an investigational anti-cancer drug for Medulloblastoma, advanced basal cell skin cancer etc.GDC-0449 is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM. Usages: Only for research, not for human use!